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With more than 100 years of scientific expertise and a presence in more than 20 countries, Daiichi Sankyo and its 15,000 employees around the world draw upon a rich legacy of innovation and a robust pipeline of promising new medicines to help people

None of them had used pentosan polysulfate for more than 6 months before the BPC-157 intravesical injections

By improving intestinal barrier function, probiotics reduce the translocation of harmful substances (e.g., LPS) into the bloodstream, thereby decreasing systemic inflammation and preventing BBB disruption (Maguire and Maguire, 2019)

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doi: 10.1001/jama.1994.03520230055038